Global Ophthalmology and Glaucoma Conference

A technique of gene therapy has been moduled with the use of special techniques and reagents. Genome sequencing has documented the importance of mobile DNA activities and major genome restructuring events at key junctures in evolution exon shuffling, changes in cis-regulatory sites, horizontal transfer, cell fusions and whole genome doublings. The natural genetic engineering functions that mediate genome restructuring are activated by multiple stimuli, in particular by events similar to those found in the DNA record, microbial infection and interspecific hybridization leading to the formation of allotetraploids. These molecular genetic discoveries plus a consideration of how mobile DNA rearrangements increase the efficiency of generating functional genomic novelties, make it possible to formulate a 21st century view of interactive evolutionary processes. This view integrates contemporary knowledge of the molecular basis of genetic change, major genome events in evolution and stimuli that activate DNA restructuring with classical cytogenetic understanding about the role of hybridization in species diversification. This clear understanding has made it possible to actually visualize the DNA restructuring under the microscope when specific stimuli aid the patients DNA to go through a hybridization technique. The final imprint of the DNA to be restructured is already present within the morphogenetic field of the patient’s serum; these qualities are further strengthened to place the DNA into the patient’s body through injections.